Review





Similar Products

animal cultured cells  (Invent Biotechnologies)
94
Invent Biotechnologies animal cultured cells
Animal Cultured Cells, supplied by Invent Biotechnologies, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/animal cultured cells/product/Invent Biotechnologies
Average 94 stars, based on 1 article reviews
animal cultured cells - by Bioz Stars, 2026-03
94/100 stars
  Buy from Supplier
erythrocyte custom sedimentation kit  (Miltenyi Biotec)
94
Miltenyi Biotec erythrocyte custom sedimentation kit
Erythrocyte Custom Sedimentation Kit, supplied by Miltenyi Biotec, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/erythrocyte custom sedimentation kit/product/Miltenyi Biotec
Average 94 stars, based on 1 article reviews
erythrocyte custom sedimentation kit - by Bioz Stars, 2026-03
94/100 stars
  Buy from Supplier
jetquick™ blood cell culture dna midiprep kit  (Thermo Fisher)
90
Thermo Fisher jetquick™ blood cell culture dna midiprep kit
Jetquick™ Blood Cell Culture Dna Midiprep Kit, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/jetquick™ blood cell culture dna midiprep kit/product/Thermo Fisher
Average 90 stars, based on 1 article reviews
jetquick™ blood cell culture dna midiprep kit - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier
culture media  (Valiant Co Ltd)
94
Valiant Co Ltd culture media
Culture Media, supplied by Valiant Co Ltd, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/culture media/product/Valiant Co Ltd
Average 94 stars, based on 1 article reviews
culture media - by Bioz Stars, 2026-03
94/100 stars
  Buy from Supplier
custom buffy coat lrsc pbmc isolation kit  (Miltenyi Biotec)
94
Miltenyi Biotec custom buffy coat lrsc pbmc isolation kit
Custom Buffy Coat Lrsc Pbmc Isolation Kit, supplied by Miltenyi Biotec, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/custom buffy coat lrsc pbmc isolation kit/product/Miltenyi Biotec
Average 94 stars, based on 1 article reviews
custom buffy coat lrsc pbmc isolation kit - by Bioz Stars, 2026-03
94/100 stars
  Buy from Supplier
minute detergent-free protein extraction kit for animal tissues and cultured cells  (Invent Biotechnologies)
94
Invent Biotechnologies minute detergent-free protein extraction kit for animal tissues and cultured cells
Minute Detergent Free Protein Extraction Kit For Animal Tissues And Cultured Cells, supplied by Invent Biotechnologies, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/minute detergent-free protein extraction kit for animal tissues and cultured cells/product/Invent Biotechnologies
Average 94 stars, based on 1 article reviews
minute detergent-free protein extraction kit for animal tissues and cultured cells - by Bioz Stars, 2026-03
94/100 stars
  Buy from Supplier
human hcc organoid culture kit  (MedChemExpress)
94
MedChemExpress human hcc organoid culture kit
Clinical relevance of SMOX , CERS1 , and SPHK1 expression and combining effects of sorafenib with spermine or sphingosine in <t>HCC</t> organoids. (A-B) The overall survival rates of liver cancer patients in TCGA were plotted according to the expression levels of the SMOX metabolic enzyme of spermine (A) and the CERS1 and SPHK1 metabolic enzymes of sphingosine (B) using KM Plotter. (C-D) The relative gene expression of SMOX (C) and SPHK1 (D) in normal (left) and tumor (right) tissues from adrenal cancer (Adrenal), acute myeloid leukemia (AML), bladder cancer (Bladder), breast cancer (Breast), colon cancer (Colon), esophageal cancer (Esoph), liver cancer (Liver), lung adenocarcinoma (LUAD), lung squamous cell carcinoma (LUSQ), ovary cancer (Ovary), pancreatic cancer (Pancreas), prostate cancer (Prostate), rectal cancer (Rectum), renal clear cell cancer (RCC), renal CH (RCH), renal PA (RPA), skin cancer (Skin), stomach cancer (Stomach), testis cancer (Testis), thyroid cancer (Thyroid), uterine CS cancer (UCS), and uterine EC (UEC). *: Mann-Whitney p<0.05 and expression >10 in tumor or normal tissue. (E-F) Patient-derived <t>HCC</t> <t>SNU-423-CO</t> organoids were treated with sorafenib with and without spermine or sphingosine for 6 days. (E) Representative images were obtained using a confocal microscope (TS100, Nikon, Tokyo, Japan). Scale bar, 50 μm. ( F ) Organoid formation efficiency and cell viability were assessed by CellTiter-Glo 3D assay. The relative organoid cell viability was plotted. Data are presented as the mean ± SD. ** p < 0.01; *** p < 0.001.
Human Hcc Organoid Culture Kit, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/human hcc organoid culture kit/product/MedChemExpress
Average 94 stars, based on 1 article reviews
human hcc organoid culture kit - by Bioz Stars, 2026-03
94/100 stars
  Buy from Supplier

Image Search Results


Clinical relevance of SMOX , CERS1 , and SPHK1 expression and combining effects of sorafenib with spermine or sphingosine in HCC organoids. (A-B) The overall survival rates of liver cancer patients in TCGA were plotted according to the expression levels of the SMOX metabolic enzyme of spermine (A) and the CERS1 and SPHK1 metabolic enzymes of sphingosine (B) using KM Plotter. (C-D) The relative gene expression of SMOX (C) and SPHK1 (D) in normal (left) and tumor (right) tissues from adrenal cancer (Adrenal), acute myeloid leukemia (AML), bladder cancer (Bladder), breast cancer (Breast), colon cancer (Colon), esophageal cancer (Esoph), liver cancer (Liver), lung adenocarcinoma (LUAD), lung squamous cell carcinoma (LUSQ), ovary cancer (Ovary), pancreatic cancer (Pancreas), prostate cancer (Prostate), rectal cancer (Rectum), renal clear cell cancer (RCC), renal CH (RCH), renal PA (RPA), skin cancer (Skin), stomach cancer (Stomach), testis cancer (Testis), thyroid cancer (Thyroid), uterine CS cancer (UCS), and uterine EC (UEC). *: Mann-Whitney p<0.05 and expression >10 in tumor or normal tissue. (E-F) Patient-derived HCC SNU-423-CO organoids were treated with sorafenib with and without spermine or sphingosine for 6 days. (E) Representative images were obtained using a confocal microscope (TS100, Nikon, Tokyo, Japan). Scale bar, 50 μm. ( F ) Organoid formation efficiency and cell viability were assessed by CellTiter-Glo 3D assay. The relative organoid cell viability was plotted. Data are presented as the mean ± SD. ** p < 0.01; *** p < 0.001.

Journal: International Journal of Biological Sciences

Article Title: Combining sorafenib with spermine and sphingosine synergistically enhances anticancer efficacy by modulating metabolic pathways and gut microbiome in hepatocellular carcinoma

doi: 10.7150/ijbs.118753

Figure Lengend Snippet: Clinical relevance of SMOX , CERS1 , and SPHK1 expression and combining effects of sorafenib with spermine or sphingosine in HCC organoids. (A-B) The overall survival rates of liver cancer patients in TCGA were plotted according to the expression levels of the SMOX metabolic enzyme of spermine (A) and the CERS1 and SPHK1 metabolic enzymes of sphingosine (B) using KM Plotter. (C-D) The relative gene expression of SMOX (C) and SPHK1 (D) in normal (left) and tumor (right) tissues from adrenal cancer (Adrenal), acute myeloid leukemia (AML), bladder cancer (Bladder), breast cancer (Breast), colon cancer (Colon), esophageal cancer (Esoph), liver cancer (Liver), lung adenocarcinoma (LUAD), lung squamous cell carcinoma (LUSQ), ovary cancer (Ovary), pancreatic cancer (Pancreas), prostate cancer (Prostate), rectal cancer (Rectum), renal clear cell cancer (RCC), renal CH (RCH), renal PA (RPA), skin cancer (Skin), stomach cancer (Stomach), testis cancer (Testis), thyroid cancer (Thyroid), uterine CS cancer (UCS), and uterine EC (UEC). *: Mann-Whitney p<0.05 and expression >10 in tumor or normal tissue. (E-F) Patient-derived HCC SNU-423-CO organoids were treated with sorafenib with and without spermine or sphingosine for 6 days. (E) Representative images were obtained using a confocal microscope (TS100, Nikon, Tokyo, Japan). Scale bar, 50 μm. ( F ) Organoid formation efficiency and cell viability were assessed by CellTiter-Glo 3D assay. The relative organoid cell viability was plotted. Data are presented as the mean ± SD. ** p < 0.01; *** p < 0.001.

Article Snippet: Patient-derived HCC SNU-423-CO organoids were obtained from KCLB (Seoul, Korea) and maintained using the human HCC organoid culture kit (Med Chem Express, Princeton, NJ, USA), supplemented with 50 ng/ml EGF, 100 ng/ml FGF, 25 ng/ml HGF, 10 mM forskolin, 1 × B27, 10 mM nicotinamide, 5 mM A83-01, 1.25 mM N-acetylcysteine, and 50 mg/ml primocin .

Techniques: Expressing, Gene Expression, MANN-WHITNEY, Derivative Assay, Microscopy